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Carbajo Martínez, Rodrigo José Author

Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C

  • Kettle J.G.
  • Bagal S.K.
  • Bickerton S.
  • Bodnarchuk M.S.
  • Breed J.
  • Carbajo R.J.
  • Cassar D.J.
  • Chakraborty A.
  • Cosulich S.
  • Cumming I.
  • Davies M.
  • Eatherton A.
  • Evans L.
  • Feron L.
  • Fillery S.
  • Gleave E.S.
  • Goldberg F.W.
  • Harlfinger S.
  • Hanson L.
  • Howard M.
  • Howells R.
  • Jackson A.
  • Kemmitt P.
  • Kingston J.K.
  • Lamont S.
  • Lewis H.J.
  • Li S.
  • Liu L.
  • Ogg D.
  • Phillips C.
  • Polanski R.
  • Robb G.
  • Robinson D.
  • Ross S.
  • Smith J.M.
  • Tonge M.
  • Whiteley R.
  • Yang J.
  • Zhang L.
  • Zhao X.
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JOURNAL OF MEDICINAL CHEMISTRY - 14/5/2020

10.1021/acs.jmedchem.9b01720

Cite count: 18 (Scopus)
  • JCR Impact Factor: 7.446 (2020)
  • CiteScore: 10.6 (2020)
  • SJR: 2.01 (2020
  • SNIP: 1.791 (2020
  • JCR 5-year Impact Factor: 7.319
  • JCR Categories: CHEMISTRY, MEDICINAL

Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments

  • Guéret S.M.
  • Thavam S.
  • Carbajo R.J.
  • Potowski M.
  • Larsson N.
  • Dahl G.
  • Dellsén A.
  • Grossmann T.N.
  • Plowright A.T.
  • Valeur E.
  • Lemurell M.
  • Waldmann H.
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Journal of the American Chemical Society - 11/3/2020

10.1021/jacs.0c00269

Cite count: 13 (Scopus)
  • JCR Impact Factor: 15.419 (2020)
  • CiteScore: 25.1 (2020)
  • SJR: 7.115 (2020
  • SNIP: 2.605 (2020
  • JCR 5-year Impact Factor: 15.801
  • JCR Categories: CHEMISTRY, MULTIDISCIPLINARY

Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist

  • Scott J.S.
  • Moss T.A.
  • Balazs A.
  • Barlaam B.
  • Breed J.
  • Carbajo R.J.
  • Chiarparin E.
  • Davey P.R.J.
  • Delpuech O.
  • Fawell S.
  • Fisher D.I.
  • Gagrica S.
  • Gangl E.T.
  • Grebe T.
  • Greenwood R.D.
  • Hande S.
  • Hatoum-Mokdad H.
  • Herlihy K.
  • Hughes S.
  • Hunt T.A.
  • Huynh H.
  • Janbon S.L.M.
  • Johnson T.
  • Kavanagh S.
  • Klinowska T.
  • Lawson M.
  • Lister A.S.
  • Marden S.
  • McGinnity D.F.
  • Morrow C.J.
  • Nissink J.W.M.
  • O'Donovan D.H.
  • Peng B.
  • Polanski R.
  • Stead D.S.
  • Stokes S.
  • Thakur K.
  • Throner S.R.
  • Tucker M.J.
  • Varnes J.
  • Wang H.
  • Wilson D.M.
  • Wu D.
  • Wu Y.
  • Yang B.
  • Yang W.
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JOURNAL OF MEDICINAL CHEMISTRY - 10/12/2020

10.1021/acs.jmedchem.0c01163

Cite count: 8 (Scopus)
  • JCR Impact Factor: 7.446 (2020)
  • CiteScore: 10.6 (2020)
  • SJR: 2.01 (2020
  • SNIP: 1.791 (2020
  • JCR 5-year Impact Factor: 7.319
  • JCR Categories: CHEMISTRY, MEDICINAL

Tricyclic Indazoles - A Novel Class of Selective Estrogen Receptor Degrader Antagonists

  • Scott J.
  • Bailey A.
  • Buttar D.
  • Carbajo R.
  • Curwen J.
  • Davey P.
  • Davies R.
  • Degorce S.
  • Donald C.
  • Gangl E.
  • Greenwood R.
  • Groombridge S.
  • Johnson T.
  • Lamont S.
  • Lawson M.
  • Lister A.
  • Morrow C.
  • Moss T.
  • Pink J.
  • Polanski R.
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JOURNAL OF MEDICINAL CHEMISTRY - 14/2/2019

10.1021/acs.jmedchem.8b01837

Cite count: 19 (Scopus)
  • SJR Quartile: Q1
  • JCR Impact Factor: 6.205 (2019)
  • CiteScore: 10.6 (2020)
  • SJR: 2.093 (2019
  • SNIP: 1.686 (2019
  • JCR 5-year Impact Factor: 6.521
  • JCR Categories: CHEMISTRY, MEDICINAL
  • SJR Categories: Drug Discovery (Q1); Molecular Medicine (Q1)

Free Ligand 1D NMR Conformational Signatures to Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles

  • Balazs A.
  • Carbajo R.
  • Davies N.
  • Dong Y.
  • Hird A.
  • Johannes J.
  • Lamb M.
  • McCoull W.
  • Raubo P.
  • Robb G.
  • Packer M.
  • Chiarparin E.
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JOURNAL OF MEDICINAL CHEMISTRY - 14/11/2019

10.1021/acs.jmedchem.9b00716

Cite count: 16 (Scopus)
  • SJR Quartile: Q1
  • JCR Impact Factor: 6.205 (2019)
  • CiteScore: 10.6 (2020)
  • SJR: 2.093 (2019
  • SNIP: 1.686 (2019
  • JCR 5-year Impact Factor: 6.521
  • JCR Categories: CHEMISTRY, MEDICINAL
  • SJR Categories: Drug Discovery (Q1); Molecular Medicine (Q1)

Building Bridges in a Series of Estrogen Receptor Degraders: An Application of Metathesis in Medicinal Chemistry

  • Scott J.
  • Breed J.
  • Carbajo R.
  • Davey P.
  • Greenwood R.
  • Huynh H.
  • Klinowska T.
  • Morrow C.
  • Moss T.
  • Polanski R.
  • Nissink J.
  • Varnes J.
  • Yang B.
... View more Collapse

ACS Medicinal Chemistry Letters - 10/10/2019

10.1021/acsmedchemlett.9b00370

Cite count: 4 (Scopus)
  • SJR Quartile: Q1
  • JCR Impact Factor: 3.975 (2019)
  • JCR 5-year Impact Factor: 3.881
  • JCR Categories: CHEMISTRY, MEDICINAL
  • SJR Categories: Drug Discovery (Q1); Organic Chemistry (Q1); Biochemistry (Q2)

Observing an Antisense Drug Complex in Intact Human Cells by in-Cell NMR Spectroscopy

  • Schlagnitweit J.
  • Friebe Sandoz S.
  • Jaworski A.
  • Guzzetti I.
  • Aussenac F.
  • Carbajo R.
  • Chiarparin E.
  • Pell A.
  • Petzold K.
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CHEMBIOCHEM - 1/10/2019

10.1002/cbic.201900297

Cite count: 12 (Scopus)
  • SJR Quartile: Q1
  • JCR Impact Factor: 2.576 (2019)
  • CiteScore: 4.7 (2020)
  • SJR: 1.009 (2019
  • SNIP: 0.657 (2019
  • JCR 5-year Impact Factor: 2.626
  • JCR Categories: BIOCHEMISTRY & MOLECULAR BIOLOGY
  • SJR Categories: Organic Chemistry (Q1); Biochemistry (Q2); Molecular Biology (Q2); Molecular Medicine (Q2)

Discovery of a Series of 5-Azaquinazolines as Orally Efficacious IRAK4 Inhibitors Targeting MyD88L265P Mutant Diffuse Large B Cell Lymphoma

  • Degorce S.
  • Anjum R.
  • Bloecher A.
  • Carbajo R.
  • Dillman K.
  • Drew L.
  • Halsall C.
  • Lenz E.
  • Lindsay N.
  • Mayo M.
  • Pink J.
  • Robb G.
  • Rosen A.
  • Scott J.
  • Xue Y.
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JOURNAL OF MEDICINAL CHEMISTRY - 1/1/2019

10.1021/acs.jmedchem.9b01346

Cite count: 8 (Scopus)
  • SJR Quartile: Q1
  • JCR Impact Factor: 6.205 (2019)
  • CiteScore: 10.6 (2020)
  • SJR: 2.093 (2019
  • SNIP: 1.686 (2019
  • JCR 5-year Impact Factor: 6.521
  • JCR Categories: CHEMISTRY, MEDICINAL
  • SJR Categories: Drug Discovery (Q1); Molecular Medicine (Q1)

Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC to Provide Insight into Small Molecule Targeting of BCL6

  • McCoull W.
  • Cheung T.
  • Anderson E.
  • Barton P.
  • Burgess J.
  • Byth K.
  • Cao Q.
  • Castaldi M.
  • Chen H.
  • Chiarparin E.
  • Carbajo R.
  • Code E.
  • Cowan S.
  • Davey P.
  • Ferguson A.
  • Fillery S.
  • Fuller N.
  • Gao N.
  • Hargreaves D.
  • Howard M.
  • Hu J.
  • Kawatkar A.
  • Kemmitt P.
  • Leo E.
  • Molina D.
  • O'Connell N.
  • Petteruti P.
  • Rasmusson T.
  • Raubo P.
  • Rawlins P.
  • Ricchiuto P.
  • Robb G.
  • Schenone M.
  • Waring M.
  • Zinda M.
  • Fawell S.
  • Wilson D.
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ACS Chemical Biology - 16/11/2018

10.1021/acschembio.8b00698

Cite count: 64 (Scopus)
  • SJR Quartile: Q1
  • JCR Impact Factor: 4.374 (2018)
  • CiteScore: 7.6 (2020)
  • SJR: 2.296 (2018
  • SNIP: 1.095 (2018
  • JCR 5-year Impact Factor: 4.698
  • JCR Categories: BIOCHEMISTRY & MOLECULAR BIOLOGY
  • SJR Categories: Biochemistry (Q1); Medicine (miscellaneous) (Q1); Molecular Medicine (Q1)

Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors

  • McCoull W.
  • Abrams R.
  • Anderson E.
  • Blades K.
  • Barton P.
  • Box M.
  • Burgess J.
  • Byth K.
  • Cao Q.
  • Chuaqui C.
  • Carbajo R.
  • Cheung T.
  • Code E.
  • Ferguson A.
  • Fillery S.
  • Fuller N.
  • Gangl E.
  • Gao N.
  • Grist M.
  • Hargreaves D.
  • Howard M.
  • Hu J.
  • Kemmitt P.
  • Nelson J.
  • O’Connell N.
  • Prince D.
  • Raubo P.
  • Rawlins P.
  • Robb G.
  • Shi J.
  • Waring M.
  • Whittaker D.
  • Wylot M.
  • Zhu X.
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JOURNAL OF MEDICINAL CHEMISTRY - 25/5/2017

10.1021/acs.jmedchem.7b00359

Cite count: 38 (Scopus)
  • SJR Quartile: Q1
  • JCR Impact Factor: 6.253 (2017)
  • CiteScore: 10.6 (2020)
  • SJR: 2.567 (2017
  • SNIP: 1.789 (2017
  • JCR 5-year Impact Factor: 5.9
  • JCR Categories: CHEMISTRY, MEDICINAL
  • SJR Categories: Drug Discovery (Q1); Molecular Medicine (Q1)

Aplicación de métodos de rmn de detección inversa a través de 1h y 31p a la identificación de moléculas complejas y núcleos de gamma baja

  • Rodrigo José Carbajo Martínez
  • Fernando Lopez-Ortiz

1999

Cite count:
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Erratum: Free ligand 1D NMR conformational signatures to enhance structure based drug design of a Mcl-1 inhibitor (AZD5991) and other synthetic macrocycles (Journal of Medicinal Chemistry (2019) 62:21 (9418-9437) DOI: 10.1021/acs.jmedchem.9b00716)

  • Balazs A.Y.S.
  • Carbajo R.J.
  • Davies N.L.
  • Dong Y.
  • Hird A.W.
  • Johannes J.W.
  • Lamb M.L.
  • McCoull W.
  • Raubo P.
  • Robb G.R.
  • Packer M.J.
  • Chiarparin E.
... View more Collapse

JOURNAL OF MEDICINAL CHEMISTRY - 1/1/2021

10.1021/acs.jmedchem.1c00273

Cite count:
  • JCR Impact Factor: 8.039 (2021)
  • CiteScore: 10.6 (2020)
  • SJR: 2.01 (2020
  • SNIP: 1.791 (2020
  • JCR 5-year Impact Factor: 7.897
  • JCR Categories: CHEMISTRY, MEDICINAL

Scopus: 24

Web of Science: 5

Scopus: 47

Web of Science: 4

Last data update: 5/11/24 6:23 AM
Next scheduled update: 5/18/24 3:00 AM