Chemogenetic inhibition of locus coeruleus to rostromedial tegmental nucleus noradrenergic pathway increases light cycle ethanol drinking in male and female mice and blunts ethanol-induced CTA |
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Insula Dynorphin and Kappa Opioid Receptor Systems Regulate Alcohol Drinking in a Sex-Specific Manner in Mice |
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Lateral hypothalamus-projecting noradrenergic locus coeruleus pathway modulates binge-like ethanol drinking in male and female TH-ires-cre mice |
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Activation of locus coeruleus to rostromedial tegmental nucleus (RMTg) noradrenergic pathway blunts binge-like ethanol drinking and induces aversive responses in mice |
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The kappa opioid receptor modulates GABA neuron excitability and synaptic transmission in midbrainprojections from the insular cortex |
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The melanocortin system as a potential target for treating alcohol use disorders: A review of pre-clinical data |
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A preliminary, open-label study of naltrexone and bupropion combination therapy for treating binge drinking in human subjects |
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Distinct and Overlapping Patterns of Acute Ethanol-Induced C-Fos Activation in Two Inbred Replicate Lines of Mice Selected for Drinking to High Blood Ethanol Concentrations |
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Bupropion, Alone and in Combination with Naltrexone, Blunts Binge-Like Ethanol Drinking and Intake Following Chronic Intermittent Access to Ethanol in Male C57BL/6J Mice |
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Extended Amygdala to Ventral Tegmental Area Corticotropin-Releasing Factor Circuit Controls Binge Ethanol Intake |
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The Role of Orexin Signaling in the Ventral Tegmental Area and Central Amygdala in Modulating Binge-Like Ethanol Drinking Behavior |
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Nucleus accumbens MC4-R stimulation reduces food and ethanol intake in adult rats regardless of binge-like ethanol exposure during adolescence |
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Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala |
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Lateral hypothalamic melanocortin receptor signaling modulates binge-like ethanol drinking in C57BL/6J mice |
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Lateral hypothalamus GABAergic neurons modulate consummatory behaviors regardless of the caloric content or biological relevance of the consumed stimuli |
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Evidence that Melanocortin Receptor Agonist Melanotan-II Synergistically Augments the Ability of Naltrexone to Blunt Binge-Like Ethanol Intake in Male C57BL/6J Mice |
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Binge-Like Consumption of Ethanol and Other Salient Reinforcers is Blocked by Orexin-1 Receptor Inhibition and Leads to a Reduction of Hypothalamic Orexin Immunoreactivity |
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The protective effects of the melanocortin receptor (MCR) agonist, melanotan-II (MTII), against binge-like ethanol drinking are facilitated by deletion of the MC3 receptor in mice |
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"Drinking in the dark" (DID) procedures: A model of binge-like ethanol drinking in non-dependent mice |
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Targeting central melanocortin receptors: A promising novel approach for treating alcohol abuse disorders |
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Decreased Immunoreactivity of the Polypeptide Precursor Pro-Opiomelanocortin (POMC) and the Prohormone Convertase PC1/3 After Chronic Ethanol Exposure in Sprague-Dawley Rats |
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MC4-R signaling within the nucleus accumbens shell, but not the lateral hypothalamus, modulates ethanol palatability in rats |
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Repeated cycles of binge-like ethanol (EtOH)-drinking in male C57BL/6J mice augments subsequent voluntary etoh intake but not other dependence-like phenotypes |
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Adolescent binge-like ethanol exposure reduces basal ?-MSH expression in the hypothalamus and the amygdala of adult rats |
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Control of food intake by MC4-R signaling in the lateral hypothalamus, nucleus accumbens shell and ventral tegmental area: Interactions with ethanol |
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Central neuropeptide y modulates binge-like ethanol drinking in C57BL/6J mice via Y1 and Y2 receptors |
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Corticotropin releasing factor signaling in the central amygdala is recruited during binge-like ethanol consumption in C57BL/6J mice |
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Neuropeptide y signaling modulates the expression of ethanol-induced behavioral sensitization in mice |
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Assessment of voluntary ethanol consumption and the effects of a melanocortin (MC) receptor agonist on ethanol intake in mutant C57BL/6J mice lacking the MC-4 receptor |
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CRF-1 antagonist and CRF-2 agonist decrease binge-like ethanol drinking in c57bl/6j mice independent of the HPA axis |
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Ethanol-induced increase of agouti-related protein (AgRP) immunoreactivity in the arcuate nucleus of the hypothalamus of C57BL/6J, but not 129/SvJ, inbred mice |
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Corticotropin-releasing factor (CRF) sensitization of ethanol withdrawal-induced anxiety-like behavior is brain site specific and mediated by CRF-1 receptors: Relation to stress-induced sensitization |
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Deletion of agouti-related protein blunts ethanol self-administration and binge-like drinking in mice |
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Decreased immunoreactivity of the melanocortin neuropeptide ?-melanocyte-stimulating hormone (?-MSH) after chronic ethanol exposure in Sprague-Dawley rats |
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Repeated lipopolysaccharide (LPS) or cytokine treatments sensitize ethanol withdrawal-induced anxiety-like behavior |
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Long-lasting reductions of rthanol drinking, enhanced ethanol-induced sedation, and decreased c-fos expression in the edinger-westphal nucleus in wistar rats exposed to the organophosphate chlorpyrifos |
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The amygdala regulates the antianxiety sensitization effect of flumazenil during repeated chronic ethanol or repeated stress |
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Reduction in repeated ethanol-withdrawal-induced anxiety-like behavior by site-selective injections of 5-HT1A and 5-HT2C ligands |
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Lateral parabrachial lesions disrupt paraoxon-induced conditioned flavor avoidance |
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Prior multiple ethanol withdrawals enhance stress-induced anxiety-like behavior: Inhibition by CRF1- and benzodiazepine-receptor antagonists and a 5-HT1a-receptor agonist |
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Effects of melanocortin receptor activation and blockade on ethanol intake: A possible role for the melanocortin-4 receptor |
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Lateral parabrachial lesions impair lithium chloride-induced aversive responses but not saccharin-induced flavor preference |
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Central neuropeptide Y alters ethanol-induced sedation,but not ethanol intake, in C57BL/6 mice |
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MTII-induced reduction of voluntary ethanol drinking is blocked by pretreatment with AgRP-(83-132) |
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Alcoholism and obesity: Overlapping neuropeptide pathways? |
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Induction of a brainstem correlate of conditioned taste aversion expression: Role of the pontine parabrachial nucleus |
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Lateral parabrachial lesions impair taste aversion learning induced by blood-borne visceral stimuli |
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cFos induction during conditioned taste aversion expression varies with aversion strength |
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