| A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1 |
|
| Organometallic Glutathione S-Transferase Inhibitors |
|
| Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme |
|
| Evolution of negative cooperativity in glutathione transferase enabled preservation of enzyme function |
|
| Glutathione transferases and neurodegenerative diseases |
|
| The impact of nitric oxide toxicity on the evolution of the glutathione transferase superfamily: A proposal for an evolutionary driving force |
|
| A new target for gold(I) compounds: Glutathione-S-transferase inhibition by auranofin |
|
| Glutathione S-transferase alpha 1 risk polymorphism and increased bilateral thalamus mean diffusivity in schizophrenia |
|
| Identifying and Characterizing Binding Sites on the Irreversible Inhibition of Human Glutathione S-Transferase P1-1 by S-Thiocarbamoylation |
|
| Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation |
|
| Diuretic drug binding to human glutathione transferase P1-1: Potential role of Cys-101 revealed in the double mutant C47S/Y108V |
|
| Silencing of GSTP1, a prostate cancer prognostic gene, by the estrogen receptor-? and endothelial nitric oxide synthase complex |
|
| Treatment of doxorubicin-resistant MCF7/Dx cells with nitric oxide causes histone glutathionylation and reversal of drug resistance |
|
| Rational design of an organometallic glutathione transferase inhibitor |
|
| Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: Structure-thermodynamic relationships and thermal stability |
|
| Monomer-dimer equilibrium in glutathione transferases: A critical re-examination |
|
| The Anti-cancer Drug Chlorambucil as a Substrate for the Human Polymorphic Enzyme Glutathione Transferase P1-1: Kinetic Properties and Crystallographic Characterisation of Allelic Variants |
|
| Glutathione transferases and glutathionylated hemoglobin in workers exposed to low doses of 1,3-butadiene |
|
| Electrostatic association of glutathione transferase to the nuclear membrane: Evidence of an enzyme defense barrier at the nuclear envelope |
|
| Organometallic ruthenium inhibitors of glutathione-S-transferase P1-1 as anticancer drugs |
|
| Calorimetric and structural studies of the nitric oxide carrier S-nitrosoglutathione bound to human glutathione transferase P1-1 |
|
| Cooperativity and pseudo-cooperativity in the glutathione S-transferase from Plasmodium falciparum |
|
| Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo |
|
| Exploration of in vitro pro-drug activation and futile cycling by glutathione S-transferases: Thiol ester hydrolysis and inhibitor maturation |
|
| Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin |
|
| Purified promyelocytic leukemia coiled-coil aggregates as a tetramer displaying low ?-helical content |
|
| Thermodynamic Description of the Effect of the Mutation Y49F on Human Glutathione Transferase P1-1 in Binding with Glutathione and the Inhibitor S-Hexylglutathione |
|
| Glutathione transferase P1-1: Self-preservation of an anti-cancer enzyme |
|
| Glutathione Transferase Superfamily Behaves Like Storage Proteins for Dinitrosyl-Diglutathionyl-Iron Complex in Heterogeneous Systems |
|
| The specific interaction of dinitrosyl-diglutathionyl-iron complex, a natural NO carrier, with the glutathione transferase superfamily: Suggestion for an evolutionary pressure in the direction of the storage of nitric oxide |
|
| Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: Structural and functional consequences |
|
| GSTB1-1 from Proteus mirabilis: A snapshot of an enzyme in the evolutionary pathway from a redox enzyme to a conjugating enzyme |
|
| Antioxidant enzymes in blood of patients with Friedreich's ataxia |
|
| Evolutionary strategy for optimization of GSH binding and catalysis in Alpha, Pi, Mu and theta glutathione transferases |
|
| Evolution of functional diversity as observed through structural studies of glutathione transferases |
|
| Exit of products from the active site of human glutathione transferase P1-1 is promoted by valine 10 |
|
| Limited proteolysis as a powerful tool for probing flexible oligopeptide portions among different classes of glutathione transferases |
|
| Human Glutathione Transferase T2-2 Discloses Some Evolutionary Strategies for Optimization of Substrate Binding to the Active Site of Glutathione Transferases |
|
| Human Glutathione Transferase P1-1 and Nitric Oxide Carriers. A new role for an old enzyme |
|
| Valine 10 may act as a driver for product release from the active site of human glutathione transferase P1-1 |
|
| Lack of glutathione conjugation to adriamycin in human breast cancer MCF-7/DOX cells: Inhibition of glutathione s-transferase p1-1 by glutathione conjugates from anthracyclines |
|
| The ligandin (non-substrate) binding site of human pi class glutathione transferase is located in the electrophile binding site (H-site) |
|
| Temperature adaptation of glutathione S-transferase P1-1. A case for homotropic regulation of substrate binding |
|
| Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis |
|
| Proton release on binding of glutathione to Alpha, Mu and Delta class glutathione transferases |
|
| International GST (Glutathione Transferase) Workshop, Rome, Italy, 7-10 Novmber, 1997: Preface |
|
| Flexibility of helix 2 in the human glutathione transferase P1-1: Time- resolved fluorescence spectroscopy |
|
| Evidence for an induced-fit mechanism operating in pi class glutathione transferases |
|
| Structural and functional consequences of haloenol lactone inactivation of murine and human glutathione S-transferase |
|
| Proton release upon glutathione binding to glutathione transferase P1- 1: Kinetic analysis of a multistep glutathione binding process |
|
| Solution structure of glutathione bound to human glutathione transferase P1-1: Comparison of NMR measurements with the crystal structure |
|
| Mutations of Gly to Ala in human glutathione transferase P1-1 affect helix 2 (G-site) and induce positive cooperativity in the binding of glutathione |
|
| Shifting substrate specificity of human glutathione transferase (from class Pi to class Alpha) by a single point mutation |
|
| Purification and characterization of a novel alpha-class glutathione transferase from human liver |
|
| Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme |
|
| Interactions of ?, ?-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1 |
|
| The glutathione conjugate of ethacrynic acid can bind to human pi class glutathione transferase P1-1 in two different modes |
|
| The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution |
|
| The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate |
|
| Catalytic mechanism and role of hydroxyl residues in the active site of theta class glutathione s-transferases investigation of ser-9 and tyr-113 in a glutathione s-transferase from the australian sheep blowfly, lucilia cuprina |
|
| Structural flexibility modulates the activity of human glutathione transferase P1-1: Role of helix 2 flexibility in the catalytic mechanism |
|
| Interaction of glutathione transferase P1-1 with captan and captafol |
|
| Site-directed mutagenesis of human glutathione transferase P1-1. Mutation of Cys-47 induces a positive cooperativity in glutathione transferase P1-1 |
|
| Site-directed mutagenesis of human glutathione transferase P1-1. Spectral, kinetic, and structural properties of Cys-47 and Lys-54 mutants |
|
| Are the Steady State Kinetics of Glutathione Transferase Always Dependent on the Deprotonation of the Bound Glutathione?. New Insights in the Kinetic Mechanism of GST-P-1-1 |
|
| Colorimetric and fluorometric assays of glutathione transferase based on 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole |
|
| Peculiar spectroscopic and kinetic properties of Cys-47 in human placental glutathione transferase. Evidence for an atypical thiolate ion pair near the active site |
|
| Three-dimensional structure of class ? glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 Å resolution |
|
| Chemical modification of human placental glutathione transferase by pyridoxal 5?-phosphate |
|
| Glutathione S-transferase in differentiating erythroleukemia cells |
|
| Insulin-dependent release of 5′-nucleotidase and alkaline phosphatase from liver plasma membranes |
|
| Interaction of glutathione transferase from horse erythrocytes with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole |
|
| Redox forms of human placenta glutathione transferase |
|
| Monoclonal antibodies against human placental glutathione transferase (class ?) |
|
| Crystallization of glutathione S-transferase from human placenta |
|
| Identification of a highly reactive sulphydryl group in human placental glutathione transferase by a site-directed fluorescent reagent |
|
| Differential activity of human, rat, mouse and bacteria glutathione transferase isoenzymes towards 4-nitroquinoline 1-oxide |
|
| Identification of glutathione transferase isoenzymes of tumour and non tumour human kidney |
|
| Ketimine rings: Useful detectors of enzymatic activities in solution and on polyacrylamide gel. Detection of l-amino acid oxidase, glutamine transaminase, pantetheinase, and acylase I |
|
| Selenium independent glutathione peroxidase activity associated with cationic forms of glutathione transferase in human heart |
|
| Serum aspartate aminotransferase activity in patients with acute viral hepatitis evaluation of isoenzymatic levels |
|
| Detection of glutathione transferase activity on polyacrylamide gels |
|
| A spectrophotometric method for determination of aspartate amino-transferase with 5,5'-dithiobis-(2-nitrobenzoic acid) |
|
