| Thought leader: Emerging trends for bioprocessing |
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| Professor Daniel I.C. Wang: A Legacy of Education, Innovation, Publication, and Leadership |
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| Preface to the republication of the 2006 review article, “Professor Daniel I. C. Wang: A Legacy of Education, Innovation, Publication, and Leadership” |
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| Chinese scientists and US leadership in the life sciences |
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| Why We Need Continuous Pharmaceutical Manufacturing and How to Make It Happen |
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| Biotech leaders call for free press |
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| Leveraging Industry-Academia Collaborations in Adaptive Biomedical Innovation |
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| A novel vortex flow reactor for the purification of B-phycoerythrin from Porphyridium cruentum |
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| The future of industrial bioprocessing: Batch or continuous? |
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| The dynamics of innovation ecosystems: A case study of the US biofuel market |
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| End-to-end continuous manufacturing of pharmaceuticals: Integrated synthesis, purification, and final dosage formation |
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| Microcrystalline cellulose powder tableting via networked cellulose-based gel material |
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| Regenerative medicine: Learning from past examples |
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| Lessons from innovation in drug-device combination products |
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| Light induced fluorescence for predicting API content in tablets: Sampling and error |
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| Effects of electrostatic charging on pharmaceutical powder blending homogeneity |
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| Quantification of lubricant activity of magnesium stearate by atomic force microscopy |
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| Studies on protein adsorption in a vortex flow reactor |
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| Professor Daniel I.C. Wang: A legacy of education, innovation, publication, and leadership |
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| Computer-aided material balancing for prediction of fermentation parameters |
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| A review on the continuous blending of powders |
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| Uncertainty analysis of penicillin V production using Monte Carlo simulation |
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| Nondestructive and on-line monitoring of tablets using light-induced flourescence technology |
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| Application of Vortex Flow Adsorption Technology to Intein-Mediated Recovery of Recombinant Human ?1-Antitrypsin |
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| Application of a Fluorescence Sensor for Miniscale On-line Monitoring of Powder Mixing Kinetics |
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| The reactivity and oxidation pathway of cysteine 232 in recombinant human ?1-antitrypsin |
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| Relationship between protein structure and methionine oxidation in recombinant human ?1-antitrypsin |
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| Continuous desulfurization of dibenzothiophene with Rhodococcus rhodochrous IGTS8 (ATCC 53968) |
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| Immunoadsorption model for a novel fluidized-bed blood detoxification device |
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| Development of a peptide mapping procedure to identify and quantify methionine oxidation in recombinant human ?1-antitrypsin |
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| Modeling of the mixing behavior of the novel fluidized extracorporeal immunoadsorber |
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| Real time and noninvasive monitoring of dry powder blend homogeneity |
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| Analysis of a Taylor-Poiseuille vortex flow reactor -- II: Reactor modeling and performance assessment using glucose-fructose isomerization as test reaction |
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| A study on intra-particle diffusion effects in enzymatic reactions: Glucose-fructose isomerization |
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| Performance of a continuous Taylor-Couette-Poiseuille vortex flow enzymic reactor with suspended particles |
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| Measurement of heat evolution and correlation with oxygen consumption during microbial growth |
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| Therapeutic blood detoxification via an immunoadsorptive fluidized bed |
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| Regional heparinization via simultaneous separation and reaction in a novel Taylor-Couette flow device |
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| Large-scale production of pharmaceutical-grade plasmid DNA for gene therapy: Problems and bottlenecks |
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| Ex vivo evaluation of a Taylor-Couette flow, immobilized heparinase I device for clinical application |
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| Heparan sulfate mediates bFGF transport through basement membrane by diffusion with rapid reversible binding |
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| RTD analysis of a novel Taylor-Couette flow device for blood detoxification |
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| Preparative purification of supercoiled plasmid DNA using anion- exchange chromatography |
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| Effects of oxygen on recombinant protein expression |
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| Pyranose ring flexibility. Mapping of physical data for iduronate in continuous conformational space |
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| Immobilization of oligonucleotides on a large pore support for plasmid purification by triplex affinity interaction |
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| Purification of plasmids by triplex affinity interaction |
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| Active learning from process data |
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| Analysis of a Taylor-Poiseuille vortex flow reactor-I: Flow patterns and mass transfer characteristics |
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| Process simulation for recombinant protein production: Cost estimation and sensitivity analysis for heparinase I expressed in Escherichia coli |
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| Heparinase III from Flavobacterium heparinum: Cloning and recombinant expression in Escherichia coli |
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| Heparinase I from Flavobacterium heparinum. Identification of a critical histidine residue essential for catalysis as probed by chemical modification and site-directed mutagenesis |
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| Expression in Escherichia coli, purification and characterization of heparinase I from Flavobacterium heparinum |
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| Heparinase I from Flavobacterium heparinum: Mapping and characterization of the heparin binding domain |
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| Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation |
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| Complex flexibility of the transforming growth factor ? superfamily |
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| Heparinase I from Flavobacterium heparinum: The Role of the Cysteine Residue in Catalysis as Probed by Chemical Modification and Site-Directed Mutagenesis |
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| Enzymatic degradation of glycosaminogiycans |
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| Axial dispersion in Taylor?Couette flow |
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| Are we prepared for animal cell technology in the 21st century? |
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| Continuous monitoring of nitrogenase activity in Azotobacter vinelandii fermentation using off?gas mass spectrometry |
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| A stereochemical approach to pyranose ring flexibility: Its implications for the conformation of dermatan sulfate |
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| Heparinase inhibits neovascularization |
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| Gene therapy: Biotech’s n + 1 technology: What they are teaching at MIT’s sloan school of management |
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| Cloning and expression of heparinase I gene from Flavobacterium heparinum |
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| Study of protein transmission through ultrafiltration membranes |
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| A pH profile control of beer fermentation using a knowledge-based system |
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| Kinetics of immobilized heparinase in human blood |
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| Design and evalution of control strategies for high cell density fermentations |
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| Recovery of alkaline proteases by membrane filtration - Effect of membrane type and addition of submicron sized charged particles |
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| Fermentation monitoring |
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| Comparison of an electrochemiluminescent homogenous immunoassay and an ELISA for monitoring productivity in mammalian cell bioreactors |
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| Nutrient and metabolite gradients in mammalian cell hollow fiber bioreactors |
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| Model of oxygen transport limitations in hollow fiber bioreactors |
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| Quantitative description of ultrafiltration in a rotating filtration device |
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| Specific plate assay for bacterial heparinase |
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| Clathrate hydrate formation enhances near-critical and supercritical solvent extraction equilibria |
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| Immobilized mammalian cell cultivation in hollow fiber bioreactors |
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| Effect of pressure on an enzymatic reaction in a supercritical fluid |
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| Optimization and simulation of continuous affinity-recycle extraction (care). |
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| An overview of continuous protein purification processes |
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| Mammalian cell and protein distributions in ultrafiltration hollow fiber bioreactors |
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| Intracellular lytic enzyme systems and their use for disruption of Escherichia coli. |
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| Release of ?-galactosidase from E. coli by a plasmid containing a temperature sensitive lytic function |
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| Esterification?coupled extraction of organic acids: Partition enhancement and underlying reaction and distribution equilibria |
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| Mathematical modelling of the continuous affinity-recycle extraction purification technique |
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| Production of ethanol by Clostridium thermosaccharolyticum: I. Effect of cell recycle and environmental parameters |
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| Production of ethanol by Clostridium thermosaccharolyticum: II. A quantitative model describing product distributions |
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| Bioprocess simulation: An integrated approach to process development |
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| Measurement and Model Prediction of Solubilities of Pure Fatty Acids, Pure Triglycerides, and Mixtures of Triglycerides in Supercritical Carbon Dioxide |
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| Immobilized Heparin Lyase System for Blood Deheparinization |
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| A Combined Microbial/Chemical Synthesis of (+)-(R)-Methyloxirane Having High Enantiomeric Excess |
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| Large scale preparation and characterization of mucopolysaccharase contamination free heparinase |
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| Polysaccharide lyases |
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| Influence of environmental factors in the production of R(-)-1, 2-propanediol by clostridium thermosaccharolyticum |
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| Continuous affinity-recycle extraction: A novel protein separation technique |
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| L?Serine Production from Glycine and Methanol Using Free and Entrapped Cells of Pseudomonas AM 1 |
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| L-glutamine enzyme electrode for on-line mammalian cell culture process control |
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| Removal of the anticoagulant activities of the low molecular weight heparin fractions and fragments with flavobacterial heparinase |
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| Oxygen limitation on L-serine production in a hollow-fiber bioreactor |
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| Production of Acetic Acid from Hydrogen and Carbon Dioxide by Clostridium Species Atcc 29797 |
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| A novel fermentation: The production of R(-)-l, 2-propanediol and acetol by clostridium thermosaccharol yticum |
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| Purification and characterization of heparinase from Flavobacterium heparinum |
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| Selective production of phenylalanine from phenylpyruvate using growing cells of Corynebacteriumglutamicum |
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| Effect of antifoam agents and efficiency of cleaning procedures on the cross-flow filtration of microbial suspensions |
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| A novel approach for neutralizing low molecular weight heparin fragments |
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| Computer controlled fed-batch fermentation of the methylotroph Pseudomonas AM1 |
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| An immobilized microbial heparinase for blood deheparinization |
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| High-resolution differential thermometry in flowing aqueous solutions |
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| ALPHA-GLUCOSIDASE SYNTHESIS IN BATCH AND CONTINUOUS CULTURE OF SACCHAROMYCES-CEREVISIAE |
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| Editorial |
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| Inaugural editorial |
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| Growth monitoring and control through computer?aided on?line mass balancing in a fed?batch penicillin fermentation |
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| Bioreactors: Design and operation |
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| Microbial fermentative preparation of l-[15N2]lysine and its tracer: Application to serum amino acid kinetic studies |
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| Growth monitoring and control in complex medium: A case study employing fed?batch penicillin fermentation and computer?aided on?line mass balancing |
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| Direct demonstration of lactate-acrylate interconversion in clostridium propionicum |
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| Direct monitoring of the liquid and gas phases during a fermentation in a computer-mass-spectrometer-fermentor system |
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| Heparinase: in vivo activity and immunogenicity in rabbits |
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| Studies on the overproduction of indole-containing metabolites by a methanol-utilizing yeast - Hansenula polymorpha |
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| Mode of action of heparin lyase on heparin |
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| Differential anticoagulant activity of heparin fragments prepared using microbial heparinase |
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| Regulation of heparinase synthesis in Flavobacterium heparinum |
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| In vivo activity of microbial heparinase |
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| An enzymatic system for removing heparin in extracorporeal therapy |
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| Expression of a proline-enriched protein in Escherichia coli |
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| Production of maltase by wild type and a constitutive mutant of Saccharomyces italicus |
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| CONTINUOUS HHO-H-2 DETERMINATION IN H2O SOLUTION BY A COMPUTER-CONTROLLED MASS-SPECTROMETER |
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| Regeneration of NAD(P)H Using Glucose 6-Sulfate and Glucose-6-phosphate Dehydrogenase |
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| Heparinase production by Flavobacterium heparinum |
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| Single?cell protein production from spent sulfite liquor utilizing cell?recycle and computer monitoring |
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| Biodegradation of sodium sulfite liquor (NaSSL) and sodium lignosulfonate (NaLS) by a mixed culture of microorganisms |
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| Methanol inhibition in continuous culture of Hansenula polymorpha |
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| Formation of short-chain fatty acids from H2 and CO2 by a mixed culture of bacteria |
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| Acrylate fermentations. |
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| Fermentation science: basic and applied research needs. Roundtable discussion. |
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| Fermentation of cellulose and fatty acids with enrichments from sewage sludge |
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| Thermal Enzyme Probe with Differential Temperature Measurements in a Laminar Flow-Through Cell |
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| Continuous monitoring of fermentation outlet gas using a computer coupled MS |
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| Single-cell protein: Engineering, economics, and utilization in foods |
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| Temporarily immobilized microorganisms: Rapid measurements using a mass spectrometer |
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| ANAEROBIC BIOMASS DEGRADATION TO PRODUCE SUGARS, FUELS AND CHEMICALS. |
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| Computer control of bakers' yeast production |
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| Indirect fermentation measurements as a basis for control |
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| On-line gas analysis for material balances and control |
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| Computer application in fermentation technology. A perspective |
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| CONTINUOUS CULTURE OF MICROORGANISMS: AN OVERVIEW AND PERSPECTIVE |
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| Simultaneous cellulose hydrolysis and ethanol production by a cellulolytic anaerobic bacterium |
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| Measurement of cell mass concentration with a continuous?flow viscometer |
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| Multi-stage digestion of municipal solid waste to fuel gas |
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| Acetate kinase production by Escherichia coli during steady-state and transient growth in continuous culture |
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| The application of dynamic calorimetry for monitoring growth of Saccharomyces cerevisiae |
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| Biomethanation: Anaerobic fermentation of CO2, H2 and CO to methane |
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| Streptococcus mutans Dextransucrase: A Review |
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| Preparation and properties of immobilized methanol oxidase |
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| Distribution of dextransucrase in Streptococcus mutans and observations on the effect of soluble dextran on dextransucrase activities |
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| Computer?aided material balancing for prediction of fermentation parameters |
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| Theoretical conversion yields for penicillin synthesis |
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| Measurement and Synthesis of Insoluble and Soluble Dextran by Streptococcus mutans |
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| Computer?aided baker's yeast fermentations |
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| An assessment of single cell protein from methanol-grown yeast |
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| A continuous assay for an intracellular enzyme: The analysis of acetate kinase in Escherichia coli |
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| Experiments and calculations concerning a thermal enzyme probe |
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| Growth of Enterobacter aerogenes in a chemostat with double nutrient limitations |
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| Continuous Culture Studies on the Growth and Physiology of Streptococcus mutans |
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| Production of gramicidin S synthetases by Bacillus brevis in continuous culture |
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| Application of dynamic calorimetry for monitoring fermentation processes |
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| Fuel gas production by anaerobic digestion of kelp |
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| Fuel gas recovery from controlled landfilling of municipal wastes |
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| Transient response of Enterobacter aerogenes under a dual nutrient limitation in a chemostat |
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| Thermophilic anaerobic digestion of cellulosic waste |
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| Penicillin amidase and penicillinase production in nitrogen- and sulfur-limited chemostats |
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| Thermophilic Anaerobic Digestion of Solid Waste for Fuel Gas Production |
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| An In Vitro Assay to Measure Early Calcium Loss from Surface Enamel |
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| Enzyme catalysis in the presence of nonaqueous solvents using chloroperoxidase |
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| A Defined Continuous Culture Medium for Streptococcus mutans |
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| Isolation and characterization of a thermotolerant methanol utilizing yeast |
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| Penicillin amidase production by bacillus megaterium |
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| Microbial Utilization of Methanol |
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| Measurement of heat evolution and correlation with oxygen consumption during microbial growth |
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