| Specific effects on the thyroid relevant for performing a dietary cumulative risk assessment of pesticide residues: 2024 update |
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| Occupational risk assessment of glutaraldehyde through personal air monitoring in a hospital setting |
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| Guidance on protocol development for EFSA generic scientific assessments |
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| Implementation of effect biomarkers in human biomonitoring studies: A systematic approach synergizing toxicological and epidemiological knowledge |
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| Effect of perinatal exposure to glyphosate and its mixture with 2,4-D and dicamba on rat dam kidney and thyroid function and offspring's health |
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| A mixture of 13 pesticides, contaminants, and food additives below individual NOAELs produces histopathological and organ weight changes in rats |
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| Renal tubular dysfunction in greenhouse farmers exposed to pesticides unveiled by a panel of molecular biomarkers of kidney injury |
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| Genetic variants of antioxidant and xenobiotic metabolizing enzymes and their association with prostate cancer: A meta-analysis and functional in silico analysis |
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| Effect of prenatal exposure to organophosphates and pyrethroid pesticides on neonatal anthropometric measures and gestational age |
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| Statement of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on the design and conduct of groundwater monitoring studies supporting groundwater exposure assessments of pesticides |
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| Occupational exposure to pesticides as a potential risk factor for epilepsy |
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| Common mechanisms of toxicity in pesticides |
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| Pesticides and tremor: An overview of association, mechanisms and confounders |
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| Development of adverse outcome pathways relevant for the identification of substances having endocrine disruption properties Uterine adenocarcinoma as adverse outcome |
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| Re‐evaluation of the existing health‐based guidance values for copper and exposure assessment from all sources |
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| The questionnaire design process in the European Human Biomonitoring Initiative (HBM4EU) |
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| Editorial: Anthropogens, lifestyle and pathophysiology of chronic diseases: From mutual interplay to translational research and personalized medicine |
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| Inhibitor binding to topoisomerase II leading to infant leukaemia |
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| Genetic variants of antioxidant enzymes and environmental exposures as molecular biomarkers associated with the risk and aggressiveness of bladder cancer |
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| Application of AOPs to assist regulatory assessment of chemical risks – Case studies, needs and recommendations |
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| Guidance on the use of the benchmark dose approach in risk assessment |
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| Scientific opinion on toxicity of pyrethroid common metabolites |
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| Statement on the active substance flupyradifurone |
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| Statement on the active substance acetamiprid |
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| Evaluation of the generic physiologically based pharmacokinetic model (PBPK) for organophosphate flame retardants (OPFRs) and neurotoxic risk assessment in children |
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| Evaluation of existing guidelines for their adequacy for the food and feed risk assessment of microorganisms obtained through synthetic biology |
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| EFSA International Workshop on RA of Combined Exposure to Multiple Chemicals |
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| In silico toxicology, a robust approach for decision-making in the context of next-generation risk assessment |
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| Integration of epidemiology with other lines of scientific evidence into pesticide risk assessment |
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| Changes in Employment Situation and Macroeconomic Indicators Linked to Mental Health Following the Recession in Spain: A Multi-level Approach |
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| The problem of risk assessment of pesticide mixtures |
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| Nutraceuticals and adverse outcome pathways |
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| Toxic contamination of nutraceuticals and food ingredients |
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| Association between crystalline silica dust exposure and silicosis development in artificial stone workers |
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| Development of Integrated Approaches to Testing and Assessment (IATA) case studies on developmental neurotoxicity (DNT) risk assessment |
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| Detrimental effects of 6 months exposure to very low doses of a mixture of six pesticides associated with chronic vitamin deficiency on rats |
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| Methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and infant’s anthropometry at birth |
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| Scientific Opinion of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on testing and interpretation of comparative in vitro metabolism studies |
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| Guidance Document on Scientific criteria for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals |
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| Opinion on the impact of non‐monotonic dose responses on EFSA′s human health risk assessments |
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| Safety of COVID-19 vaccines administered in the EU: Should we be concerned? |
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| Assessment of the combined effects of chromium and benzene on the rat neuroendocrine and immune systems |
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| Computational modelling: A new paradigm for chemical mixtures risk assessment? |
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| Guidance on technical requirements for regulated food and feed product applications to establish the presence of small particles including nanoparticles |
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| Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health |
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| Guidance on aneugenicity assessment |
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| Challenges and Scientific Prospects of the Newest Generation of mRNA-Based Vaccines against SARS-CoV-2 |
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| Validity and Reproducibility of a Food Frequency Questionnaire to Assess Nutrients Intake of Pregnant Women in the South-East of Spain |
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| A systems‐based approach to the environmental risk assessment of multiple stressors in honey bees |
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| Exposure to pesticides and childhood leukemia risk: a systematic review and meta-analysis |
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| Evaluation of conventional and non-conventional biomarkers of liver toxicity in greenhouse workers occupationally exposed to pesticides |
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| Statement on the derivation of Health‐Based Guidance Values (HBGVs) for regulated products that are also nutrients |
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| Statement of the PPR Panel on a framework for conducting the environmental exposure and risk assessment for transition metals when used as active substances in plant protection products (PPP) |
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| Cumulative dietary risk assessment of chronic acetylcholinesterase inhibition by residues of pesticides |
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| Draft for internal testing Scientific Committee guidance on appraising and integrating evidence from epidemiological studies for use in EFSA's scientific assessments |
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| Urinary levels of organophosphate pesticides and predictors of exposure in pre-school and school children living in agricultural and urban communities from south Spain |
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| Scientific Opinion of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on the genotoxic potential of triazine amine (metabolite common to several sulfonylurea active substances) |
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| The under-reported role of toxic substance exposures in the COVID-19 pandemic |
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| Evaluation of existing guidelines for their adequacy for the microbial characterisation and environmental risk assessment of microorganisms obtained through synthetic biology |
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| Statement on the translocation potential by Pseudomonas chlororaphis MA342 in plants after seed treatment of cereals and peas and assessment of the risk to humans |
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| Genetic variants in xenobiotic detoxi fication enzymes, antioxidant defenses and hormonal pathways as biomarkers of susceptibility to prostate cancer |
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| COVID-19, an opportunity to reevaluate the correlation between long-term effects of anthropogenic pollutants on viral epidemic/pandemic events and prevalence |
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| Reply to Swaen's letter regarding ‘Environmental exposure to pesticides and risk of thyroid diseases’ |
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| Cumulative dietary risk characterisation of pesticides that have acute effects on the nervous system |
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| Cumulative dietary risk characterisation of pesticides that have chronic effects on the thyroid |
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| Application of novel technologies and mechanistic data for risk assessment under the real-life risk simulation (RLRS) approach |
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| Biomonitoring of 45 inorganic elements measured in plasma from Spanish subjects: A cross-sectional study in Andalusian population |
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| Mechanisms underlying disruptive effects of pesticides on the thyroid function |
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| Childhood chromium exposure and neuropsychological development in children living in two polluted areas in southern Spain |
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| Establishment of cumulative assessment groups of pesticides for their effects on the thyroid |
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| Establishment of cumulative assessment groups of pesticides for their effects on the nervous system |
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| Overview of the effects of chemical mixtures with endocrine disrupting activity in the context of real-life risk simulation (RLRS): An integrative approach (Review) |
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| Scientific Opinion on the setting of health-based reference values for metabolites of the active substance terbuthylazine |
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| Guidance on the use of the Threshold of Toxicological Concern approach in food safety assessment |
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| Environmental exposure to pesticides and risk of thyroid diseases |
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| Biomonitoring of common organophosphate metabolites in hair and urine of children from an agricultural community |
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| Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures |
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| Scientific statement on the coverage of bats by the current pesticide risk assessment for birds and mammals |
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| Virgin Olive Oil and Health: Summary of the III International Conference on Virgin Olive Oil and Health Consensus Report, JAEN (Spain) 2018 |
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| Toxicology for real-life risk simulation - Editorial preface to this special issue |
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| Integration of epidemiological findings with mechanistic evidence in regulatory pesticide risk assessment: EFSA experiences |
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| GSTM1 gene expression and copy number variation in prostate cancer patients-Effect of chemical exposures and physical activity |
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| Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals |
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| Genotoxicity assessment of chemical mixtures |
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| Association between environmental exposure to pesticides and epilepsy |
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| Biomarkers of oxidative stress in blood of workers exposed to non-cholinesterase inhibiting pesticides |
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| Scientific Opinion about the Guidance of the Chemical Regulation Directorate (UK) on how aged sorption studies for pesticides should be conducted, analysed and used in regulatory assessments |
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| Scientific Opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) effect models for regulatory risk assessment of pesticides for aquatic organisms |
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| Scientific opinion on pesticides in foods for infants and young children |
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| Serum concentrations of organochlorine compounds and predictors of exposure in children living in agricultural communities from South-Eastern Spain |
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| Potential risks of dietary exposure to chlorpyrifos and cypermethrin from their use in fruit/vegetable crops and beef cattle productions |
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| Six months exposure to a real life mixture of 13 chemicals' below individual NOAELs induced non monotonic sex-dependent biochemical and redox status changes in rats |
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| Scientific Opinion on the state of the science on pesticide risk assessment for amphibians and reptiles |
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| Association of reproductive disorders and male congenital anomalies with environmental exposure to endocrine active pesticides |
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| Scientific Opinion of the PPR Panelon the follow-up of the findings of the External Scientific Report "Literature review of epidemiological studies linking exposure to pesticides and health effects' |
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| Toxicological interactions of pesticide mixtures: an update |
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| OECD/EFSA Workshop on Developmental Neurotoxicity (DNT): The Use of Non-Animal Test Methods for Regulatory Purposes |
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| Chemical exposure and infant leukaemia: development of an adverse outcome pathway (AOP) for aetiology and risk assessment research |
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| Determination of metalloid, metallic and mineral elements in herbal teas. Risk assessment for the consumers |
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| Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach |
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| Human exposure to chemical mixtures: Challenges for the integration of toxicology with epidemiology data in risk assessment |
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| Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia |
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| Scientific Opinion addressing the state of the science on risk assessment of plant protection products for in-soil organisms |
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| Guidance on the establishment of the residue definition for dietary risk assessment |
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| Activity and determinants of cholinesterases and paraoxonase-1 in blood of workers exposed to non-cholinesterase inhibiting pesticides |
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| Occupational pesticide exposure and adverse health effects at the clinical, hematological and biochemical level |
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| Systematic reviews on neurodevelopmental and neurodegenerative disorders linked to pesticide exposure: Methodological features and impact on risk assessment |
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| Exposure to pesticides and diabetes: A systematic review and meta-analysis |
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| Linking Pesticide Exposure with Pediatric Leukemia: Potential Underlying Mechanisms |
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| Postnatal arsenic exposure and attention impairment in school children |
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| Pre- and postnatal exposures to pesticides and neurodevelopmental effects in children living in agricultural communities from South-Eastern Spain |
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| Polymorphisms of pesticide-metabolizing genes in children living in intensive farming communities |
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| Statement on the FERA guidance proposal: 'Guidance on how aged sorption studies for pesticides should be conducted, analysed and used in regulatory assessments' (FERA, 2012) |
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| Scientific Opinion on the effect assessment for pesticides on sediment organisms in edge-of-field surface water |
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| Statement on the suitability of the BEEHAVE model for its potential use in a regulatory context and for the risk assessment of multiple stressors in honeybees at the landscape level |
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| Increased N7-methyldeoxyguanosine DNA adducts after occupational exposure to pesticides and influence of genetic polymorphisms of paraoxonase-1 and glutathione S-transferase M1 and T1 |
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| Toxicological importance of human biomonitoring of metallic and metalloid elements in different biological samples |
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| Biomonitoring of arsenic, cadmium, lead, manganese and mercury in urine and hair of children living near mining and industrial areas |
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| Scientific Opinion addressing the state of the science on risk assessment of plant protection products for non-target arthropods |
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| A systematic review of neurodevelopmental effects of prenatal and postnatal organophosphate pesticide exposure |
|
| Environmental exposure to pesticides and cancer risk in multiple human organ systems |
|
| Rapid determination of quetiapine in blood by gas chromatography-mass spectrometry. Application to post-mortem cases |
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| Scientific Opinion addressing the state of the science on risk assessment of plant protection products for non-target terrestrial plants |
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| Scientific Opinion on good modelling practice in the context of mechanistic effect models for risk assessment of plant protection products |
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| Toxic effects of pesticide mixtures at a molecular level: Their relevance to human health |
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| Scientific Opinion on the relevance of dissimilar mode of action and its appropriate application for cumulative risk assessment of pesticides residues in food |
|
| Scientific Opinion on the developmental neurotoxicity potential of acetamiprid and imidacloprid |
|
| Determination of essential elements (copper, manganese, selenium and zinc) in fish and shellfish samples. Risk and nutritional assessment and mercury-selenium balance |
|
| Modulation of the endogenous antioxidants paraoxonase-1 and urate by pesticide exposure and genetic variants of xenobiotic-metabolizing enzymes |
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| Pesticide exposure and genetic variation in xenobiotic-metabolizing enzymes interact to induce biochemical liver damage |
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| Determination of toxic elements (mercury, cadmium, lead, tin and arsenic) in fish and shellfish samples. Risk assessment for the consumers |
|
| Hair testing for cocaine and metabolites by GC/MS: criteria to quantitatively assess cocaine use |
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| Scientific Opinion on the identification of pesticides to be included in cumulative assessment groups on the basis of their toxicological profile |
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| Guidance on tiered risk assessment for plant protection products for aquatic organisms in edge-of-field surface waters |
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| Scientific Opinion on the report of the FOCUS groundwater working group (FOCUS, 2009): assessment of higher tiers EFSA Panel on Plant Protection Products and their Residues (PPR) |
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| A mechanistic overview of health associated effects of low levels of organochlorine and organophosphorous pesticides |
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| Changes in male hormone profile after occupational organophosphate exposure. A longitudinal study |
|
| Evaluation of pesticide-induced oxidative stress from a gene-environment interaction perspective |
|
| Scientific Opinion on the report of the FOCUS groundwater working group (FOCUS, 2009): assessment of lower tiers |
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| Pesticides and asthma |
|
| Association between environmental exposure to pesticides and neurodegenerative diseases |
|
| Paraoxonase-1 and clopidogrel efficacy |
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| Paraoxonase-1 and clopidogrel efficacy |
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| Biomonitorization of cadmium, chromium, manganese, nickel and lead in whole blood, urine, axillary hair and saliva in an occupationally exposed population |
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| Toxicology Teaching Medicine in the degree of |
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| Urinary levels of arsenic and heavy metals in children and adolescents living in the industrialised area of Ria of Huelva (SW Spain) |
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| Validation of a method to quantify chromium, cadmium, manganese, nickel and lead in human whole blood, urine, saliva and hair samples by electrothermal atomic absorption spectrometry |
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| Interaction between human serum esterases and environmental metal compounds |
|
| A fatal case following exposure to zinc chloride and hexachloroethane from a smoke bomb in a fire simulation at a school |
|
| Low level of exposure to pesticides leads to lung dysfunction in occupationally exposed subjects |
|
| Biomonitoring of urinary metals in a population living in the vicinity of industrial sources: A comparison with the general population of Andalusia, Spain |
|
| Plasma cholinesterase levels and health symptoms in peruvian farm workers exposed to organophosphate pesticides |
|
| A controlled study of the time-course of breath alcohol concentration after moderate ingestion of ethanol following a social drinking session |
|
| Investigation of an outbreak of acute respiratory illness due to exposure to chlorine gas in a public swimming pool |
|
| Paraoxonase-1 (PON1) as a predictor of biochemical outcomes in farmers |
|
| Changes in antioxidant enzymes in humans with long-term exposure to pesticides |
|
| Effect of metal ions and calcium on purified PON1 and PON3 from rat liver |
|
| Validation of a procedure for the gas chromatography-mass spectrometry analysis of cocaine and metabolites in pericardial fluid |
|
| Application of pericardial fluid to the analysis of morphine (heroin) and cocaine in forensic toxicology |
|
| Heavy metal concentrations in the general population of Andalusia, South of Spain - A comparison with the population within the area of influence of Aznalcollar mine spill (SW Spain) |
|
| Distribution of paraoxonase-1 gene polymorphisms and enzyme activity in a Peruvian population |
|
| Influence of exposure to pesticides on serum components and enzyme activities of cytotoxicity among intensive agriculture farmers |
|
| Changes in erythrocyte enzymes in humans long-term exposed to pesticides: Influence of several markers of individual susceptibility |
|
| Effect of long-term exposure to pesticides on plasma esterases from plastic greenhouse workers |
|
| Identification of paraoxonase 3 in rat liver microsomes: purification and biochemical properties |
|
| Paraoxonase activity and genetic polymorphisms in greenhouse workers with long term pesticide exposure |
|
| From case report to epidemiological evidence of causality in biomedical research |
|
| Teaching toxicology in health sciences in the XXI century |
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| Del case report a la evidencia epidemiológica de casualidad en investigación biodémica |
|
| Immunohistochemical evidence for the expression and induction of paraoxonase in rat liver, kidney, lung and brain tissue. implications for its physiological role |
|
| Hydrolysis of platelet-activating factor by human serum paraoxonase |
|
| Distribution profiles of paraoxonase and cholinesterase phenotypes in a Spanish population |
|
| Identification of two rat liver proteins with paraoxonase activity: biochemical evidence for the identity of paraoxonase and arylesterase |
|
| Lack of clinical symptoms in an acute arsenic poisoning: An unusual case |
|
| Human Liver Paraoxonase (PON1): Subcellular Distribution and Characterization |
|
| Acute chemical pancreatitis associated with nonfatal strychnine poisoning |
|
| Simultaneous death of twins: An environmental hazard or SIDS? [2] (multiple letters) |
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| Simultaneous death of twins: An environmental hazard or SIDS? Authors' reply |
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| Inhibition of paraoxonase activity in human liver microsomes by exposure to EDTA, metals and mercurials |
|
| Simultaneous death of twins - An environmental hazard or SIDS? |
|
| Divergent effects of classical inducers on rat plasma and microsomal fraction paraoxonase and arylesterase |
|
| Purification and characterization of paraoxon hydrolase from rat liver |
|
| Clinical and biochemical changes in greenhouse sprayers chronically exposed to pesticides |
|
| Increased risk of suicide with exposure to pesticides in an intensive agricultural area. A 12-year retrospective study |
|
| FATAL MOCLOBEMIDE OVERDOSE OR DEATH CAUSED BY SEROTONIN SYNDROME |
|
| NEUROLEPTIC MALIGNANT SYNDROME - REPLY |
|
| DIFFERENCES IN THE KINETIC-PROPERTIES, EFFECT OF CALCIUM AND SENSITIVITY TO INHIBITORS OF PARAOXON HYDROLASE ACTIVITY IN RAT PLASMA AND MICROSOMAL FRACTION FROM RAT-LIVER |
|
| ANALYSIS OF COCAINE AND METABOLITES IN BRAIN USING SOLID-PHASE EXTRACTION AND FULL-SCANNING GAS-CHROMATOGRAPHY ION-TRAP MASS-SPECTROMETRY |
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| CLINICAL AND PATHOLOGICAL FINDINGS IN FATAL 1,3-DICHLOROPROPENE INTOXICATION |
|
| PARTIAL-PURIFICATION OF PARAOXONASE FROM RAT-LIVER |
|
| CHARACTERIZATION OF PARAOXONASE ACTIVITY IN PERICARDIAL FLUID - USEFULNESS AS A MARKER OF CORONARY-DISEASE |
|
| PARAOXONASE ACTIVITY IN HUMAN PERICARDIAL FLUID - ITS RELATIONSHIP TO CORONARY-ARTERY DISEASE |
|
| DECREASE OF PHOSPHOFRUCTOKINASE ACTIVITY IN RELATION TO THE PATHOGENESIS OF TRIORTHOCRESYL-PHOSPHATE INDUCED DELAYED NEUROPATHY |
|
| APPLICATION OF THE COMBINED USE OF HPLC DIODE-ARRAY DETECTION AND CAPILLARY GC NITROGEN PHOSPHORUS DETECTION FOR THE RAPID ANALYSIS OF ILLICIT HEROIN AND COCAINE SAMPLES |
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| Study of physiological histopathologic and enzymatic parameters in sciatic nerve of triorthocresyl phosphate-treated hens |
|
| A FATAL CASE OF ORAL INGESTION OF METHANOL - DISTRIBUTION IN POSTMORTEM TISSUES AND FLUIDS INCLUDING PERICARDIAL FLUID AND VITREOUS-HUMOR |
|
| Biochemical changes during the development of organophosphorus ester-induced delayed neuropathy (OPIDN) their implication in the mechanism of action |
|
| DECREASED PHOSPHOFRUCTOKINASE ACTIVITY DURING THE DEVELOPMENT OF TRIORTHOCRESYL-PHOSPHATE-INDUCED DELAYED NEUROPATHY |
|
| Determination of glutathione and glutathione peroxidase activity after death. |
|
| Hepatotoxicity mechanisms |
|
| MECHANISMS OF HEPATOTOXICITY |
|
| LACK OF INHIBITION OF GLYCOLYTIC-ENZYMES BY THE NEUROTOXIC ORGANO-PHOSPHORUS COMPOUNDS MIPAFOX AND METHAMIDOFOS |
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