| Structure and dynamics of the cyanobacterial regulator SipA |
|
| Targeting NUPR1-dependent stress granules formation to induce synthetic lethality in Kras<sup>G12D</sup>-driven tumors |
|
| Three-dimensional solution structure, dynamics and binding of thioredoxin m from Pisum sativum |
|
| The intrinsically disordered, epigenetic factor RYBP binds to the citrullinating enzyme PADI4 in cancer cells |
|
| New insights into cancer: MDM2 binds to the citrullinating enzyme PADI4 |
|
| Paul F. Fitzpatrick: A life of editorial duties and elucidating the mechanism of enzyme action |
|
| Intrinsically Disordered Chromatin Protein NUPR1 Binds to the Enzyme PADI4 |
|
| Folding of the nascent polypeptide chain of a histidine phosphocarrier protein in vitro |
|
| The armadillo-repeat domain of Plakophilin 1 binds to human enzyme PADI4 |
|
| Conformational Stability of the N-Terminal Region of MDM2 |
|
| Human Enzyme PADI4 Binds to the Nuclear Carrier Importin α3 |
|
| Biochemical and biophysical characterization of PADI4 supports its involvement in cancer |
|
| Deciphering the Binding of the Nuclear Localization Sequence of Myc Protein to the Nuclear Carrier Importin α3 |
|
| NUPR1 protects against hyperPARylation-dependent cell death |
|
| Phosphorylation of Thr9 Affects the Folding Landscape of the N-Terminal Segment of Human AGT Enhancing Protein Aggregation of Disease-Causing Mutants |
|
| A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation |
|
| Structural insights into choline-O-sulfatase reveal the molecular determinants for ligand binding |
|
| The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3 |
|
| Crowding Effects on the Structure and Dynamics of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1 |
|
| The armadillo-repeat domain of plakophilin 1 binds the C-terminal sterile alpha motif (SAM) of p73 |
|
| The histidine phosphocarrier kinase/phosphorylase from bacillus subtilis is an oligomer in solution with a high thermal stability |
|
| Intrinsically disordered protein NUPR1 binds to the armadillo-repeat domain of Plakophilin 1 |
|
| NUPR1 inhibitor ZZW-115 induces ferroptosis in a mitochondria-dependent manner |
|
| An N-terminal half fragment of the histidine phosphocarrier protein, HPr, is disordered but binds to HPr partners and shows antibacterial properties |
|
| Design of inhibitors of the intrinsically disordered protein nupr1: Balance between drug affinity and target function |
|
| Residual helicity at the active site of the histidine phosphocarrier, HPr, modulates binding affinity to its natural partners |
|
| The muscle-relaxing C-terminal peptide from troponin I populates a nascent helix, facilitating binding to tropomyosin with a potent therapeutic effect |
|
| Discrimination of sulfated isomers of chondroitin sulfate disaccharides by HILIC-MS |
|
| Investigation of action pattern of a novel chondroitin sulfate/dermatan sulfate 4-O-endosulfatase |
|
| The isolated GTPase-activating-protein-related domain of neurofibromin-1 has a low conformational stability in solution |
|
| ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents |
|
| The isolated armadillo-repeat domain of Plakophilin 1 is a monomer in solution with a low conformational stability |
|
| Intrinsically disordered proteins in biology: One for all, all for one |
|
| Dynamics of the intrinsically disordered inhibitor IF7 of glutamine synthetase in isolation and in complex with its partner |
|
| The Paralogue of the Intrinsically Disordered Nuclear Protein 1 Has a Nuclear Localization Sequence that Binds to Human Importin α3 |
|
| A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin |
|
| Human importin ?3 and its N-terminal truncated form, without the importin-?-binding domain, are oligomeric species with a low conformational stability in solution. |
|
| Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis |
|
| The C-terminal SAM domain of p73 binds to the N terminus of MDM2 |
|
| Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability |
|
| Kinetic and thermodynamic effects of phosphorylation on p53 binding to MDM2 |
|
| Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma |
|
| Dynamics of the intrinsically disordered protein NUPR1 in isolation and in its fuzzy complexes with DNA and prothymosin α |
|
| Targeting intrinsically disordered proteins involved in cancer |
|
| Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm |
|
| A group II intron-encoded protein interacts with the cellular replicative machinery through the β-sliding clamp |
|
| Dendrimers as Competitors of Protein-Protein Interactions of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1 |
|
| The isolated C-terminal nuclear localization sequence of the breast cancer metastasis suppressor 1 is disordered |
|
| The chromatin nuclear protein NUPR1L is intrinsically disordered and binds to the same proteins as its paralogue |
|
| Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1) |
|
| Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis |
|
| The C Terminus of the Ribosomal-Associated Protein LrtA is an Intrinsically Disordered Oligomer |
|
| The Cyanobacterial Ribosomal-Associated Protein LrtA from <i>Synechocystis</i> sp. PCC 6803 Is an Oligomeric Protein in Solution with Chameleonic Sequence Properties |
|
| The Cyanobacterial Ribosomal-Associated Protein LrtA from Synechocystis sp. PCC 6803 Is an Oligomeric Protein in Solution with Chameleonic Sequence Properties |
|
| The histidine phosphocarrier protein, HPr, binds to the highly thermostable regulator of sigma D protein, Rsd, and its isolated helical fragments |
|
| Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution |
|
| The isolated, twenty-three-residue-long, N-terminal region of the glutamine synthetase inactivating factor binds to its target |
|
| An introduction to the special issue on biomolecular NMR |
|
| Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of polycomb RING1B |
|
| The PipX Protein, When Not Bound to Its Targets, Has Its Signaling C-Terminal Helix in a Flexed Conformation |
|
| Intrinsically disordered inhibitor of glutamine synthetase is a functional protein with random-coil-like pK<inf>a</inf> values |
|
| Trifluoroethanol-induced conformational transition of the C-terminal sterile alpha motif (SAM) of human p73 |
|
| Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism |
|
| Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma |
|
| The Monomeric Species of the Regulatory Domain of Tyrosine Hydroxylase Has a Low Conformational Stability |
|
| Dissecting the Binding between Glutamine Synthetase and Its Two Natively Unfolded Protein Inhibitors |
|
| Determinants of the pK<inf>a</inf> values of ionizable residues in an intrinsically disordered protein |
|
| The chondroitin sulfate/dermatan sulfate 4-O-endosulfatase from marine bacterium Vibrio sp FC509 is a dimeric species: Biophysical characterization of an endosulfatase |
|
| Human COA3 Is an Oligomeric Highly Flexible Protein in Solution |
|
| Erratum: The carboxy-terminal domain of Erb1 Is a seven-bladed β-propeller that binds RNA (PLoS ONE (2015) 10:4 (e0123463) DOI: 10.1371/journal.pone.0123463) |
|
| The carboxy-terminal domain of Erb1 is α seven-bladed β-propeller that binds RNA |
|
| Functional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1 |
|
| Biophysical analysis of the MHR motif in folding and domain swapping of the HIV capsid protein C-terminal domain |
|
| Structural dissection of the C-terminal sterile alpha motif (SAM) of human p73 |
|
| Biochemical and mutational studies of allantoinase from Bacillus licheniformis CECT 20T |
|
| Electrostatic effects in the folding of the SH3 domain of the c-Src tyrosine kinase: PH-dependence in 3D-domain swapping and amyloid formation Julio Bacarizo1 |
|
| Evidence supporting the existence of a NUPR1-like family of helix-loop-helix chromatin proteins related to, yet distinct from, AT hook-containing HMG proteins |
|
| The isolated N terminus of Ring1B is a well-folded, monomeric fragment with native-like structure |
|
| The Histidine-Phosphocarrier Protein of the Phosphoenolpyruvate: Sugar Phosphotransferase System of Bacillus sphaericus Self-Associates |
|
| BRMS1<inf>51-98</inf> and BRMS1<inf>51-84</inf> are crystal oligomeric coiled coils with different oligomerization states, which behave as disordered protein fragments in solution |
|
| The HIV-1 capsid protein as a drug target: Recent advances and future prospects |
|
| Falling down: Landscape and kinetics of one-dimensional protein folding |
|
| An N-terminally truncated mutant of human chemokine CXCL14 has biological activity |
|
| NMR as a tool to identify and characterize protein folding intermediates |
|
| NS3 protease from hepatitis C virus: Biophysical studies on an intrinsically disordered protein domain |
|
| Protein folding and stability: A Prague cemetery |
|
| Deciphering the binding between Nupr1 and MSL1 and their DNA-repairing activity. |
|
| Peptides as inhibitors of the first phosphorylation step of the streptomyces coelicolor phosphoenolpyruvate: Sugar phosphotransferase system |
|
| The C-terminal sterile alpha motif (SAM) domain of human p73 is a highly dynamic protein, which acquires high thermal stability through a decrease in backbone flexibility |
|
| Non-canonical residues of the marginally stable monomeric ubiquitin conjugase from goldfish are involved in binding to the C terminus of Ring 1B |
|
| Insights into the mechanism of activation of the phosphorylation-independent response regulator NblR. Role of residues Cys69 and Cys96 |
|
| Biophysical characterization of the isolated C-terminal region of the transient receptor potential vanilloid 1 |
|
| Mutation of Ser-50 and Cys-66 in Snapin modulates protein structure and stability |
|
| Stability and binding of the phosphorylated species of the N-terminal domain of enzyme i and the histidine phosphocarrier protein from the Streptomyces coelicolor phosphoenolpyruvate:sugar phosphotransferase system |
|
| Turbulent times in southern European science |
|
| Larger helical populations in peptides derived from the dimerization helix of the capsid protein of HIV-1 results in peptide binding toward regions other than the "hotspot" interface |
|
| Rationally designed interfacial peptides are efficient in vitro inhibitors of HIV-1 capsid assembly with antiviral activity |
|
| The structure of BRMS1 nuclear export signal and SNX6 interacting region reveals a hexamer formed by antiparallel coiled coils |
|
| Biochemical and mutational studies of the Bacillus cereus CECT 5050T formamidase support the existence of a C-E-E-K tetrad in several members of the nitrilase superfamily |
|
| The conformational stability and biophysical properties of the eukaryotic thioredoxins of Pisum sativum are not family-conserved |
|
| The inactivating factor of glutamine synthetase IF17 Is an intrinsically disordered protein, which folds upon binding to its target |
|
| N-Carbamoyl-?-alanine amidohydrolase from Agrobacterium tumefaciens C58: A promiscuous enzyme for the production of amino acids |
|
| The isolated major homology region of the HIV capsid protein is mainly unfolded in solution and binds to the intact protein |
|
| Nucleotide-induced conformational transitions in the CBS domain protein MJ0729 of Methanocaldococcus jannaschii |
|
| The N-terminal domain of the enzyme I is a monomeric well-folded protein with a low conformational stability and residual structure in the unfolded state |
|
| Folded and unfolded conformations of proteins involved in pancreatic cancer: A Layman's guide |
|
| Dendrimers as potential inhibitors of the dimerization of the capsid protein of HIV-1 |
|
| Structural characterisation of the natively unfolded enterocin EJ97 |
|
| Evidence of non-functional redundancy between two pea h-type thioredoxins by specificity and stability studies |
|
| The regulatory factor SipA is a highly stable β-II class protein with a SH3 fold |
|
| The basic helix-loop-helix region of human neurogenin 1 is a monomeric natively unfolded protein which forms a "fuzzy" complex upon DNA binding |
|
| High-recovery one-step purification of the DNA-binding protein Fur by mild guanidinium chloride treatment |
|
| Conformational stability of hepatitis C virus NS3 protease |
|
| The CBS domain protein MJ0729 of Methanocaldococcus jannaschii binds DNA |
|
| Insights into the functionality of the putative residues involved in enterocin AS-48 maturation |
|
| Pancreatic cancer: Molecular, biochemical, chemopreventive, and therapeutic aspects |
|
| The bronze age of science in Spain |
|
| Structure and conformational stability of a tetrameric thermostable N-succinylamino acid racemase |
|
| The positively charged C-terminal region of the inactivating Shaker B peptide binds to the potassium channel KcsA |
|
| Biophysical and structural studies on the capsid protein of the human immunodeficiency virus type 1: A new drug target? |
|
| The CBS domain protein MJ0729 of Methanocaldococcus jannaschii is a thermostable protein with a pH-dependent self-oligomerization |
|
| The transcriptional repressor RYBP is a natively unfolded protein which folds upon binding to DNA |
|
| Discovery of specific flavodoxin inhibitors as potential therapeutic agents against Helicobacter pylori infection |
|
| Thermodynamics of zinc binding to hepatitis C virus NS3 protease: A folding by binding event |
|
| The capsid protein of human immunodeficiency virus: Molecular recognition and design of antiviral agents: MINIREVIEW SERIES |
|
| Metal-triggered changes in the stability and secondary structure of a tetrameric dihydropyrimidinase: A biophysical characterization |
|
| p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage |
|
| Defining the epitope region of a peptide from the Streptomyces coelicolor phosphoenolpyruvate:sugar phosphotransferase system able to bind to the enzyme I |
|
| Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein |
|
| N-type inactivation of the potassium channel KcsA by the Shaker B "ball" Peptide: Mapping the inactivating peptide-binding epitope |
|
| Spain should implement a model that's known to work |
|
| Conformational stability of Helicobacter pylori flavodoxin Fit to Function at pH 5 |
|
| The family 52 ?-xylosidase from Geobacillus stearothermophilus is a dimer: Structural and biophysical characterization of a glycoside hydrolase |
|
| Into the lipid realm: Stability and thermodynamics of membrane proteins |
|
| Envelope lipids regulate the in vitro assembly of the HIV-1 capsid |
|
| Dynamics of tryptophan in the histidine-containing phosphocarrier protein of Streptomyces coelicolor: Evidence of multistate equilibrium unfolding |
|
| Isolation and characterization of a thermostable beta-xylosidase in the thermophilic bacterium Geobacillus pallidus |
|
| The Helical Structure Propensity in the First Helix of the Histidine Phosphocarrier Protein of Streptomyces coelicolor |
|
| The isolated C-terminal domain of ring 1B is a dimer made of stable, well-structured monomers |
|
| Flexibility in HIV-1 assembly subunits: Solution structure of the monomeric C-terminal domain of the capsid protein |
|
| Filling Small, Empty Protein Cavities: Structural and Energetic Consequences |
|
| p8 and prothymosin alpha: Unity is strength |
|
| Regulation of apoptosis by the p8/prothymosin alpha complex |
|
| Binding of the C-terminal domain of the HIV-1 capsid protein to lipid membranes: A biophysical characterization |
|
| Site-directed mutagenesis indicates an important role of cysteines 76 and 181 in the catalysis of hydantoin racemase from Sinorhizobium meliloti |
|
| Biophysical characterization of the enzyme I of the Streptomyces coelicolor phosphoenolpyruvate:sugar phosphotransferase system |
|
| An extensive thermodynamic characterization of the dimerization domain of the HIV-1 capsid protein |
|
| Structure and conformational stability of the enzyme I of Streptomyces coelicolor explored by FTIR and circular dichroism |
|
| HPr as a model protein in structure, interaction, folding and stability studies |
|
| Unfolding and refolding in vitro of a tetrameric, alpha-helical membrane protein: The prokaryotic potassium channel KcsA |
|
| The conformational stability and thermodynamics of Fur A (ferric uptake regulator) from Anabaena sp. PCC 7119 |
|
| The dimerization domain of the HIV-1 capsid protein binds a capsid protein-derived peptide: A biophysical characterization |
|
| The conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein: Characterization of cold denaturation and urea-protein interactions |
|
| Thermodynamic dissection of a low affinity protein-protein interface involved in human immunodeficiency virus assembly |
|
| The inactivating factor of glutamine synthetase, IF7, is a "natively unfolded" protein |
|
| The histidine-phosphocarrier protein of Streptomyces coelicolor folds by a partially folded species at low pH |
|
| Structure and dynamics of the potato carboxypeptidase inhibitor by 1H and 15N NMR |
|
| Binding of the C-terminal sterile alpha motif (SAM) domain of human p73 to lipid membranes |
|
| Biochemical analysis of the recombinant Fur (ferric uptake regulator) protein from Anabaena PCC 7119: Factors affecting its oligomerization state |
|
| Equilibrium unfolding of the C-terminal SAM domain of p73 |
|
| Equilibrium unfolding studies of the rat liver methionine adenosyltransferase III, a dimeric enzyme with intersubunit active sites |
|
| Three-dimensional solution structure and stability of thioredoxin m from spinach |
|
| Hydrogen exchange of the tetramerization domain of the human tumour suppressor p53 probed by denaturants and temperature |
|
| Human p8 Is a HMG-I/Y-like Protein with DNA Binding Activity Enhanced by Phosphorylation |
|
| Stability and folding of the protein complexes of barnase |
|
| Towards a complete description of the structural and dynamic properties of the denatured state of barnase and the role of residual structure in folding |
|
| Acquisition of native-like interactions in C-terminal fragments of barnase |
|
| Exploring the folding funnel of a polypeptide chain by biophysical studies on protein fragments |
|
| Hydrogen exchange in ribonuclease A and ribonuclease S: Evidence for residual structure in the unfolded state under native conditions |
|
| Hydrogen exchange in chymotrypsin inhibitor 2 probed by mutagenesis |
|
| Hydrogen exchange in chymotrypsin inhibitor 2 probed by denaturants and temperature |
|
| Following co-operative formation of secondary and tertiary structure in a single protein module |
|
| The folding pathway of a protein at high resolution from microseconds to seconds |
|
| Folding studies on ribonuclease A, a model protein |
|
| Towards the complete structural characterization of a protein folding pathway: The structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism |
|
| An NMR study on the β-hairpin region of barnase |
|
| Folding of a nascent polypeptide chain in vitro: Cooperative formation of structure in a protein module |
|
| Conformational pathway of the polypeptide chain of chymotrypsin inhibitor-2 growing from its N terminus in vitro. Parallels with the protein folding pathway |
|
| Search for nucleation sites in smaller fragments of chymotrypsin inhibitor 2 |
|
| Refined solution structure of bovine pancreatic Ribonuclease A by<sup>1</sup>H NMR methods. Sidechain dynamics |
|
| High-resolution three-dimensional structure of ribonuclease A in solution by nuclear magnetic resonance spectroscopy |
|
| An N-terminal fragment of barnase has residual helical structure similar to that in a refolding intermediate |
|
| Peptide group chemical shift computation |
|
| EFFECT OF ALANINE VERSUS GLYCINE IN ALPHA-HELICES ON PROTEIN STABILITY |
|
| 3D structure of bovine pancreatic ribonuclease A in aqueous solution: An approach to tertiary structure determination from a small basis of<sup>1</sup>H NMR NOE correlations |
|
| Sequential <sup>1</sup>H‐NMR assignment and solution structure of bovine pancreatic ribonuclease A |
|
