López Grancha, Matilde Author

A novel selective PKR inhibitor restores cognitive deficits and neurodegeneration in alzheimer disease experimental models

  • Lopez-Grancha M.
  • Bernardelli P.
  • Moindrot N.
  • Genet E.
  • Vincent C.
  • Roudieres V.
  • Krick A.
  • Sabuco J.F.
  • Machnik D.
  • Ibghi D.
  • Pradier L.
  • Taupin V.
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS - 1/9/2021

10.1124/jpet.121.000590

Cite count:

Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model

  • Do T.M.
  • Capdevila C.
  • Pradier L.
  • Blanchard V.
  • Lopez-Grancha M.
  • Schussler N.
  • Steinmetz A.
  • Beninga J.
  • Boulay D.
  • Dugay P.
  • Verdier P.
  • Aubin N.
  • Dargazanli G.
  • Chaves C.
  • Genet E.
  • Lossouarn Y.
  • Loux C.
  • Michoux F.
  • Moindrot N.
  • Chanut F.
  • Gury T.
  • Eyquem S.
  • Valente D.
  • Bergis O.
  • Rao E.
  • Lesuisse D.
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Molecular Therapy - Methods and Clinical Development - 11/12/2020

10.1016/j.omtm.2020.08.014

Cite count: 2 (Scopus)

The selective GSK3 inhibitor, SAR502250, displays neuroprotective activity and attenuates behavioral impairments in models of neuropsychiatric symptoms of Alzheimer’s disease in rodents

  • Griebel G.
  • Stemmelin J.
  • Lopez-Grancha M.
  • Boulay D.
  • Boquet G.
  • Slowinski F.
  • Pichat P.
  • Beeské S.
  • Tanaka S.
  • Mori A.
  • Fujimura M.
  • Eguchi J.
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Scientific Reports - 1/12/2019

10.1038/s41598-019-54557-5

Cite count: 24 (Scopus)

Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-? burden in several amyloid transgenic mouse models

  • Latta-Mahieu M.
  • Elmer B.
  • Bretteville A.
  • Wang Y.
  • Lopez-Grancha M.
  • Goniot P.
  • Moindrot N.
  • Ferrari P.
  • Blanc V.
  • Schussler N.
  • Brault E.
  • Roudières V.
  • Blanchard V.
  • Yang Z.Y.
  • Barneoud P.
  • Bertrand P.
  • Roucourt B.
  • Carmans S.
  • Bottelbergs A.
  • Mertens L.
  • Wintmolders C.
  • Larsen P.
  • Hersley C.
  • McGathey T.
  • Racke M.M.
  • Liu L.
  • Lu J.
  • O'Neill M.J.
  • Riddell D.R.
  • Ebneth A.
  • Nabel G.J.
  • Pradier L.
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GLIA - 1/3/2018

10.1002/glia.23260

Cite count: 28 (Scopus)

The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents

  • Griebel G.
  • Stemmelin J.
  • Lopez-Grancha M.
  • Fauchey V.
  • Slowinski F.
  • Pichat P.
  • Dargazanli G.
  • Abouabdellah A.
  • Cohen C.
  • Bergis O.
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Scientific Reports - 1/12/2018

10.1038/s41598-018-20895-z

Cite count: 35 (Scopus)

SAR110894, a potent histamine H3-receptor antagonist, displays disease-modifying activity in a transgenic mouse model of tauopathy

  • Delay-Goyet P.
  • Blanchard V.
  • Schussler N.
  • Lopez-Grancha M.
  • Ménager J.
  • Mary V.
  • Sultan E.
  • Buzy A.
  • Guillemot J.
  • Stemmelin J.
  • Bertrand P.
  • Rooney T.
  • Pradier L.
  • Barnéoud P.
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Alzheimer's and Dementia: Translational Research and Clinical Interventions - 1/11/2016

10.1016/j.trci.2016.10.002

Cite count: 12 (Scopus)

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

  • Griebel G.
  • Pichat P.
  • Beeske S.
  • Leroy T.
  • Redon N.
  • Jacquet A.
  • Françon D.
  • Bert L.
  • Even L.
  • Lopez-Grancha M.
  • Tolstykh T.
  • Sun F.
  • Yu Q.
  • Brittain S.
  • Arlt H.
  • He T.
  • Zhang B.
  • Wiederschain D.
  • Bertrand T.
  • Houtmann J.
  • Rak A.
  • Vallee F.
  • Michot N.
  • Auge F.
  • Menet V.
  • Bergis O.
  • George P.
  • Avenet P.
  • Mikol V.
  • Didier M.
  • Escoubet J.
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Scientific Reports - 6/1/2015

10.1038/srep07642

Cite count: 76 (Scopus)

SAR110894, a potent histamine H3-receptor antagonist, displays procognitive effects in rodents

  • Griebel G.
  • Pichat P.
  • Pruniaux M.
  • Beeské S.
  • Lopez-Grancha M.
  • Genet E.
  • Terranova J.
  • Castro A.
  • Sánchez J.
  • Black M.
  • Varty G.
  • Weiner I.
  • Arad M.
  • Barak S.
  • De Levie A.
  • Guillot E.
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PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR - 1/8/2012

10.1016/j.pbb.2012.04.004

Cite count: 39 (Scopus)

The neurokinin NK2 antagonist, saredutant, ameliorates stress-induced conditions without impairing cognition

  • Rogacki N.
  • Lopez-Grancha M.
  • Naimoli V.
  • Potestio L.
  • Stevens R.
  • Pichat P.
  • Bergis O.
  • Cohen C.
  • Varty G.
  • Griebel G.
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PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR - 1/5/2011

10.1016/j.pbb.2010.11.017

Cite count: 5 (Scopus)

Individual differences in schedule-induced polydipsia and the role of gabaergic and dopaminergic systems

  • López-Grancha M.
  • Lopez-Crespo G.
  • Sanchez-Amate M.
  • Flores P.

PSYCHOPHARMACOLOGY - 1/4/2008

10.1007/s00213-007-1059-6

Cite count: 34 (Web of Science) 30 (Scopus)

This author has no books, chapters or theses.

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This author has no patents.

This author has no reports or other types of publications.

Scopus: 12

Web of Science: 6

Scopus: 12

Web of Science: 5

Last data update: 11/20/24 2:14 AM
Next scheduled update: 11/23/24 3:00 AM