López Grancha, Matilde Author

A novel selective PKR inhibitor restores cognitive deficits and neurodegeneration in alzheimer disease experimental models

  • Lopez-Grancha M.
  • Bernardelli P.
  • Moindrot N.
  • Genet E.
  • Vincent C.
  • Roudieres V.
  • Krick A.
  • Sabuco J.F.
  • Machnik D.
  • Ibghi D.
  • Pradier L.
  • Taupin V.
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS - 1/9/2021

10.1124/jpet.121.000590

Cite count:

Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model

  • Do T.M.
  • Capdevila C.
  • Pradier L.
  • Blanchard V.
  • Lopez-Grancha M.
  • Schussler N.
  • Steinmetz A.
  • Beninga J.
  • Boulay D.
  • Dugay P.
  • Verdier P.
  • Aubin N.
  • Dargazanli G.
  • Chaves C.
  • Genet E.
  • Lossouarn Y.
  • Loux C.
  • Michoux F.
  • Moindrot N.
  • Chanut F.
  • Gury T.
  • Eyquem S.
  • Valente D.
  • Bergis O.
  • Rao E.
  • Lesuisse D.
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Molecular Therapy - Methods and Clinical Development - 11/12/2020

10.1016/j.omtm.2020.08.014

Cite count: 2 (Scopus)

The selective GSK3 inhibitor, SAR502250, displays neuroprotective activity and attenuates behavioral impairments in models of neuropsychiatric symptoms of Alzheimer’s disease in rodents

  • Griebel G.
  • Stemmelin J.
  • Lopez-Grancha M.
  • Boulay D.
  • Boquet G.
  • Slowinski F.
  • Pichat P.
  • Beeské S.
  • Tanaka S.
  • Mori A.
  • Fujimura M.
  • Eguchi J.
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Scientific Reports - 1/12/2019

10.1038/s41598-019-54557-5

Cite count: 24 (Scopus)

Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-? burden in several amyloid transgenic mouse models

  • Latta-Mahieu M.
  • Elmer B.
  • Bretteville A.
  • Wang Y.
  • Lopez-Grancha M.
  • Goniot P.
  • Moindrot N.
  • Ferrari P.
  • Blanc V.
  • Schussler N.
  • Brault E.
  • Roudières V.
  • Blanchard V.
  • Yang Z.Y.
  • Barneoud P.
  • Bertrand P.
  • Roucourt B.
  • Carmans S.
  • Bottelbergs A.
  • Mertens L.
  • Wintmolders C.
  • Larsen P.
  • Hersley C.
  • McGathey T.
  • Racke M.M.
  • Liu L.
  • Lu J.
  • O'Neill M.J.
  • Riddell D.R.
  • Ebneth A.
  • Nabel G.J.
  • Pradier L.
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GLIA - 1/3/2018

10.1002/glia.23260

Cite count: 28 (Scopus)

The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents

  • Griebel G.
  • Stemmelin J.
  • Lopez-Grancha M.
  • Fauchey V.
  • Slowinski F.
  • Pichat P.
  • Dargazanli G.
  • Abouabdellah A.
  • Cohen C.
  • Bergis O.
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Scientific Reports - 1/12/2018

10.1038/s41598-018-20895-z

Cite count: 35 (Scopus)

SAR110894, a potent histamine H3-receptor antagonist, displays disease-modifying activity in a transgenic mouse model of tauopathy

  • Delay-Goyet P.
  • Blanchard V.
  • Schussler N.
  • Lopez-Grancha M.
  • Ménager J.
  • Mary V.
  • Sultan E.
  • Buzy A.
  • Guillemot J.
  • Stemmelin J.
  • Bertrand P.
  • Rooney T.
  • Pradier L.
  • Barnéoud P.
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Alzheimer's and Dementia: Translational Research and Clinical Interventions - 1/11/2016

10.1016/j.trci.2016.10.002

Cite count: 12 (Scopus)

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

  • Griebel G.
  • Pichat P.
  • Beeske S.
  • Leroy T.
  • Redon N.
  • Jacquet A.
  • Françon D.
  • Bert L.
  • Even L.
  • Lopez-Grancha M.
  • Tolstykh T.
  • Sun F.
  • Yu Q.
  • Brittain S.
  • Arlt H.
  • He T.
  • Zhang B.
  • Wiederschain D.
  • Bertrand T.
  • Houtmann J.
  • Rak A.
  • Vallee F.
  • Michot N.
  • Auge F.
  • Menet V.
  • Bergis O.
  • George P.
  • Avenet P.
  • Mikol V.
  • Didier M.
  • Escoubet J.
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Scientific Reports - 6/1/2015

10.1038/srep07642

Cite count: 76 (Scopus)

SAR110894, a potent histamine H3-receptor antagonist, displays procognitive effects in rodents

  • Griebel G.
  • Pichat P.
  • Pruniaux M.
  • Beeské S.
  • Lopez-Grancha M.
  • Genet E.
  • Terranova J.
  • Castro A.
  • Sánchez J.
  • Black M.
  • Varty G.
  • Weiner I.
  • Arad M.
  • Barak S.
  • De Levie A.
  • Guillot E.
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PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR - 1/8/2012

10.1016/j.pbb.2012.04.004

Cite count: 39 (Scopus)

The neurokinin NK2 antagonist, saredutant, ameliorates stress-induced conditions without impairing cognition

  • Rogacki N.
  • Lopez-Grancha M.
  • Naimoli V.
  • Potestio L.
  • Stevens R.
  • Pichat P.
  • Bergis O.
  • Cohen C.
  • Varty G.
  • Griebel G.
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PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR - 1/5/2011

10.1016/j.pbb.2010.11.017

Cite count: 5 (Scopus)

Individual differences in schedule-induced polydipsia and the role of gabaergic and dopaminergic systems

  • López-Grancha M.
  • Lopez-Crespo G.
  • Sanchez-Amate M.
  • Flores P.

Psychopharmacology - 1/4/2008

10.1007/s00213-007-1059-6

Cite count: 34 (Web of Science) 30 (Scopus)

This author has no books, chapters or theses.

This author has no conferences.

This author has no patents.

This author has no reports or other types of publications.

Scopus: 12

Web of Science: 6

Scopus: 12

Web of Science: 5

Last data update: 3/23/24 4:35 AM
Next scheduled update: 3/30/24 3:00 AM